Isoniazid inhibits cyp 2e1 and so raises the levels of n -acetyl- para -benzoquinoneimine, which is the toxic metabolite of paracetamol, thus explaining the reports of toxicity experienced when both drugs are administered to some patients moulding et al.

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this retrospective cohort study demonstrated comparable completion rates between the novel three months of isoniazid and rifapentine and the less often used four months of rifampin.

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because isoniazid is the generic alternative for , there is no manufacturer-sponsored prescription assistance program for isoniazid 300 mg.

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based on their cost projections, 4 months of rifampin could be 20 less efficacious than isoniazid and still be cost-saving.


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