Isoniazid inhibits cyp 2e1 and so raises the levels of n -acetyl- para -benzoquinoneimine, which is the toxic metabolite of paracetamol, thus explaining the reports of toxicity experienced when both drugs are administered to some patients moulding et al.

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this retrospective cohort study demonstrated comparable completion rates between the novel three months of isoniazid and rifapentine and the less often used four months of rifampin.

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because isoniazid is the generic alternative for , there is no manufacturer-sponsored prescription assistance program for isoniazid 300 mg.

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be careful with glucotrol if you take aspirin or another salicylate such as magnesium choline salicylate trilisate , salsalate disalcid, others , choline salicylate arthropan , magnesium salicylate magan or bismuth subsalicylate pepto-bismol ; nonsteroidal anti-inflammatory drug nsaid such as ibuprofen motrin, advil, nuprin, others , ketoprofen orudis, orudis kt, oruvail , diclofenac voltaren, cataflam , etodolac lodine , indomethacin indocin , nabumetone relafen , oxaprozin daypro , naproxen anaprox, naprosyn, aleve and others; sulfa-based drug such as sulfamethoxazole-trimethoprim bactrim, septra , sulfisoxazole gantrisin , or sulfasalazine azulfidine ; monoamine oxidase inhibitor maoi such as isocarboxazid marplan , tranylcypromine parnate or phenelzine nardil ; beta-blocker such as propranolol inderal , atenolol tenormin , acebutolol sectral , metoprolol lopressor and others; diuretic water pill such as hydrochlorothiazide hctz, hydrodiuril , chlorothiazide diuril and others; steroid medicine such as prednisone deltasone, orasone, others , methylprednisolone medrol, others , prednisolone prelone, pediapred, others and others; phenothiazine such as chlorpromazine thorazine , fluphenazine prolixin, permitil , prochlorperazine compazine , promethazine phenergan and others; phenytoin dilantin ; isoniazid nydrazid ; prescription, over-the-counter, or herbal cough, cold, allergy or weight loss medications.

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based on their cost projections, 4 months of rifampin could be 20 less efficacious than isoniazid and still be cost-saving.

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