The approximate incidences of adverse reactions reported in pediatric patients with jra treated with oral, weekly doses of methotrexate 5 to 20 mg m wk or 0.

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make sure your dr prescribed you folic acid also or you can get it over the counter as the methotrexate will leach the folic acid out of your system, which can cause hair loss and can cause heart problems, also.

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advise patients to report to their healthcare provider if they are taking warfarin or high-dose methotrexate see warnings and precautions .

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methotrexate therapy can produce potentially fatal pulmonary toxicity, including acute or chronic interstitial pneumonitis and pulmonary fibrosis.

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methotrexate has been shown to be teratogenic; it has caused foetal death and or congenital anomalies.

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do not take this medicine with any of the following medications -medicines that treat or prevent blood clots like warfarin or heparin -methotrexate this medicine may also interact with the following medications -acetazolamide -adenosine -anagrelide -antiinflammatory drugs, nsaids like ibuprofen -aspirin-containing medicines or other salicylates -diuretics -medicines for alzheimer s disease or myasthenia gravis -medicines for diabetes that are taken by mouth -medicines for high blood pressure like ace inhibitors or beta-blockers -medicines for seizures like phenytoin or valproic acid -probenecid -sulfinpyrazone.

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